5 edition of Neurotrophic Factors (Taniguchi Symposia on Brain Sciences, No 15) found in the catalog.
February 1, 1993
Written in English
|Contributions||Eric Shooter (Editor)|
|The Physical Object|
|Number of Pages||243|
neurotrophic factor: A generic term for any of a family of substances with roles in maintenance and survival of neurons–eg, secretory proteins, nerve growth factors–see there, brain-derived growth factor, neurotrophin One area of particular interest involves neurotrophic factors (NTFs), with those of the glial cell line-derived neurotrophic factor (GDNF) family showing greatest promise. The safety and efficacy of these therapies has recently come into question. Furthermore, many of the key questions pertaining to such therapies, such as the optimal method of Cited by:
In book: Transgenic Models Neurotrophic factors do not only regulate neuronal survival but also neural differentiation, neurite outgrowth, synapse formation, transmitter synthesis and release Author: Michael Sendtner. 2. Dopaminergic neurotrophic factors. One novel therapeutic strategy under investigation is the use of neurotrophic factors, which have the potential to slow down or halt the ongoing neurodegeneration in PD by: 1.
Neurotrophic factors are agents that are important for survival, growth, or differentiation of discrete neuronal populations. Based on amino acid sequence homologies of cytokines and receptors and based on similarities in cytokine-receptor binding characteristics, neurotrophic factors can be divided into three general families. 1,2 The “neurotrophin family’’ includes nerve growth factor. The BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. In the brain, the BDNF protein is active at the.
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Jimcy Platholi, Francis S. Lee, in Handbook of Developmental Neurotoxicology (Second Edition), VII Other neurotrophic factors. Functions of neurotrophic factors outside the nervous system have been described. Glial-derived Neurotrophic Factors book factor (GDNF), a member of the transforming growth factor-β superfamily, is an kDa protein that binds to one of two.
This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field.
Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. Key Features * Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system * Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor Format: Hardcover.
Neurotrophic Factors: Methods and Protocols presents a selection of protocols and procedures which make use of cellular, tissue, and whole animal models which can be applied to the Neurotrophic Factors book of neurotrophic factors and other agents impacting on these systems. Chapters cover a wide-range of topics such as dealing with the culture of neurons.
Subsequent chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides, as well as protocols describing nanofiber- and nanoparticle-based methods for brain delivery of neurotrophic agents.
Neurotrophic Factors is devoted to neurotrophic factors and explores aspects of their structure, the regulation of their synthesis, the way in which they influence neuronal survival and differentiation, and the mechanisms of their action on a variety of neurons.
The book emphasizes the importance of. A guide to neurotrophic factors. It explores the various aspects of their structure, the regulation of their synthesis, the way in which they influence neuronal survival and differentiation, and the mechanisms of their action on a variety of neurons.
The Hardcover of the Neurotrophic Factors by Gary R. Lewin at Barnes & Noble. This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett Author: Gary R.
Lewin. The field of neurotrophic factors has witnessed exp- sive growth in the past decade. As is usual in scientific in- vation, this progress has been closely associated with methodological advances.
The introduction of molecular b- logical techniques into the neurotrophic factor field led to the discovery of new families of neurotrophic growth f. Authoritative and practical, Neurotrophic Factors: Methods and Protocols, Second Edition is a valuable resource for a wide audience of readers as they explore nervous system function and pathology.
Product details. Series: Methods in Molecular Biology (Book Format: Hardcover. Neurotrophic Factors is devoted to neurotrophic factors and explores aspects of their structure, the regulation of their synthesis, the way in which they influence neuronal survival and differentiation, and the mechanisms of their action on a variety of neurons.
The book emphasizes the importance of all these neurotrophic factors in the development and maintenance of the. Brain-derived neurotrophic factor. BDNF is the second member of the NT family that was discovered in due to its trophic effects in dorsal root ganglion cells and hippocampal and cortical neurons. It is a kDa basic protein and is one of the most potent factors that support neuronal survival, regulating neurotransmitter release and dendritic growth.Cited by: Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene.
BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor. Neurotrophic factors are found in the brain and the periphery. BDNF was first isolated from pig brain in by Yves-Alain Barde and Hans Aliases: BDNF, brain-derived neurotrophic factor.
Features: The book provides a selection of protocols and procedures using cellular, tissue, and animal models for in vivo and in vitro neurobiological research into the role of neurotrophic factors and other chemicals on the nervous system function and dysfunction.
It comprehensively reviews methods involving imaging, assays, cultures, delivery Price: $ Among these environmental cues, neurotrophic factors are secreted proteins that promote neurite outgrowth, neuronal cell differentiation and survival both in vivo and in vitro.
Nerve growth factor (NGF) is the founding and best characterized member of. item 3 Neurotrophic Factors (English) Hardcover Book Free Shipping. - Neurotrophic Factors (English) Hardcover Book Free Shipping. $ Free shipping. No ratings or reviews yet. Be the first to write a review.
Best Selling in Nonfiction. See all. Synthesizes information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. This book also examines brain development and aging, neurodegenerative disorders.
Terminology. According to the United States National Library of Medicine's medical subject headings, the term neurotrophin may be used as a synonym for neurotrophic factor, but the term neurotrophin is more generally reserved for four structurally related factors: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 InterPro: IPR Neurotrophic Factors.
Handbook of Experimental Pharmacology (Book ) Share your thoughts Complete your review. Tell readers what you thought by rating and reviewing this book. Rate it * You Rated it *Brand: Springer Berlin Heidelberg. (Factors with neurotrophic effects can also exert nootropic effects.) Exercise is an example of a neurotrophic strategy, as consistent exercise has been shown to increase hippocampal volume (the part of the brain damaged in dementia) by about 2% over one year, a substantial increase.
Find many great new & used options and get the best deals for Handbook of Experimental Pharmacology: Neurotrophic Factors Vol. (, Hardcover) at the best online prices at eBay! Free shipping for many products!Neurotrophic Factors and Major Depressive Disorder.
By Xiaobin Zhang, Jin Li, Weiwei Sha and Ru Bu. Submitted: May 30th Reviewed: September 30th Published: June 11th DOI: /Cited by: 1.Neurotrophic factors, which include the neurotrophins, the proteins related to glial cell-derived neurotrophic factor, and other secreted proteins, serve multiple roles in function and plasticity.